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Journal of Asian Natural Products Research Volume 26, 2024 - Issue 6
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Research Articles

Pharmacokinetics of cyanidin-3-O-galactoside and cyanidin-3-O-arabinoside after intravenous administration in rats

Yan Chena School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing210000, ChinaView further author information
,
Jing Zhaoa School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing210000, ChinaView further author information
,
Han-Han Lia School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing210000, ChinaView further author information
,
Wen Qianb Nanjing BRT-Biomed Company Limited, Nanjing210000, ChinaView further author information
,
Bing-Yu Zhouc Department of Pharmacy, Dongliao People’s Hospital, Liaoyuan136200, ChinaCorrespondence[email protected]
View further author information
&
Chang-Qing Yanga School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing210000, ChinaCorrespondence[email protected]
View further author information
Pages 714-725 | Received 21 May 2023, Accepted 31 Oct 2023, Published online: 11 Nov 2023
 
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Abstract

Cyanidin-3-O-galactoside and cyanidin-3-O-arabinoside (purity >98%) were isolated from black chokeberry by preparative high-performance liquid chromatography, and an animal experiment was conducted to investigate the pharmacokinetics of two anthocyanin monomers after intravenous administration. The results showed that cyanidin-3-O-galactoside has preferable druggability than cyanidin-3-O-arabinoside in pharmacokinetic area.

Disclosure statement

The authors declared no potential conflicts of interest with respect to the research, authorship, and publication of this article.

Additional information

Funding

The author(s) reported there is no funding associated with the work featured in this article.

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