Abstract
In recent years, the application of liposomes in the field of analytical chemistry has attracted more and more attention. In this paper, the preparation and characterization of liposomes are briefly summarized, and the research and application of liposomes in organic and biological substances analysis are mainly reviewed, including immobilized liposome chromatography, liposome capillary electrophoresis, liposome application in electrochemical analysis, and optical analysis. The future developments of liposomes in the assay are also prospected.
Disclosure statement
All authors declare that they have no conflict of interest.
Abbreviations | ||
AFM | = | Atomic force microscope |
Au@Ag | = | Gold-silver alloy |
BPA | = | Bisphenol A |
CE | = | Capillary electrophoresis |
CEC | = | Capillary electrophoresis chromatography |
CF | = | Carboxyfluorescein |
CT | = | Cholera toxin |
cryo-TEM | = | Cryogenic transmission electron microscope |
DLS | = | Dynamic light scattering |
ELISA | = | Enzyme-linked immunosorbent assay |
ELS | = | Evaporative light scattering |
EPC | = | Egg phosphatidylcholine |
EPE | = | Egg yolk phosphatidylethanolamine |
ESR | = | Electron spin resonance |
FFF | = | Field-flow fractionation |
FID | = | Flame ionization detection |
FRET | = | Förster resonance energy transfer |
GC | = | Gas chromatography |
GFLC | = | Gold nanoparticle/ferrocene/liposome cluster |
GM1 | = | Ganglioside |
GST | = | Glutathione S-transferase |
GUVs | = | Giant unilamellar vesicles |
HPLC | = | High performance liquid chromatography |
ILC | = | Immobilized liposome chromatography |
iPCR | = | Immuno-polymerase chain reaction |
LC | = | liposome capillary |
LCE | = | Liposome capillary electrophoresis |
LEKC | = | Liposome electrokinetic capillary chromatography |
LISA | = | Liposome immunosorbent assay |
LOD | = | Limit of detection |
LUVs | = | Large unilamellar vesicles |
MALS | = | Multi-angle light scattering |
MLVs | = | Multilamellar vesicles |
MS | = | Mass spectrometer |
MVVs | = | Multi-vesicular vesicles |
NMR | = | Nuclear magnetic resonance |
NPs; SiO2@Au@Ag | = | Au@Ag-assembled silica nanoparticles |
NSE | = | Neuron-specific enolase |
OVIs | = | Organic volatile impurities |
PC | = | Phosphatidylcholine |
PDA | = | Polydiacetylene |
PE | = | Phosphatidylethanolamine |
PEC | = | Photoelectrochemical |
PLA2 | = | Phospholipase A2 |
POPC | = | 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine |
POPG | = | 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol |
PS | = | Phosphatidylserine |
QDs | = | Quantum dots |
R6G | = | Rhodamine 6G |
RI | = | Refractive index |
scCO2 | = | Supercritical carbon dioxide |
SCFs | = | Supercritical fluids |
SEC | = | Size exclusion chromatography |
SUVs | = | Small unilamellar vesicles |
Tc | = | Lipid transition temperature |
TLC | = | Thin layer chromatography |