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Leukemia & Lymphoma Volume 48, 2007 - Issue 3
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Review

Relevant prognostic features of multiple myeloma and the new International Staging System

Morie A. Gertz Division of Hematology, Mayo Clinic, Rochester, MN, USACorrespondence[email protected]
Pages 458-468 | Received 16 Aug 2006, Accepted 08 Oct 2006, Published online: 01 Jul 2009
 
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Abstract

The new International Staging System should be reported in all future studies of multiple myeloma. However, the system fails to account for recent research findings pertaining to mechanisms of disease progression. This review describes development of the International Staging System and details prognostic factors that may further our understanding of the biology of multiple myeloma.

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