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Leukemia & Lymphoma Volume 59, 2018 - Issue 10
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Letter to the Editor

Heterochronous occurrence of microsatellite instability in multiple myeloma – an implication for a role of defective DNA mismatch repair in myelomagenesis

Kaname MiyashitaDepartment of Hematology, National Kyushu Cancer Center, Fukuoka, Japan; ;Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; ORCID Iconhttp://orcid.org/0000-0002-7461-8829View further author information
ORCID Icon,
Kei FujiiDepartment of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; View further author information
,
Youko SuehiroDepartment of Hematology, National Kyushu Cancer Center, Fukuoka, Japan; View further author information
,
Kenichi TaguchiClinical Research Institute, Cancer Genetics Laboratory, National Kyushu Cancer Center, Fukuoka, Japan; View further author information
,
Naokuni UikeDepartment of Hematology, National Kyushu Cancer Center, Fukuoka, Japan; View further author information
,
Mitsuaki A. YoshidaDepartment of Radiation Biology, Institute of Radiation Emergency Medicine, Hirosaki University, Aomori, JapanView further author information
&
Shinya OdaClinical Research Institute, Cancer Genetics Laboratory, National Kyushu Cancer Center, Fukuoka, Japan; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-9226-8511View further author information
ORCID Icon show all
Pages 2454-2459 | Received 11 Oct 2017, Accepted 07 Jan 2018, Published online: 31 Jan 2018
 
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Acknowledgments

We are grateful to P. Karran and M. Sekiguchi for helpful advice. We also thank Y. Yamada, Y. Abe and K. Muta for their expert comments. The expert assistance in DNA extraction, DNA sequencing and immunohistochemistry by Y. Ogata, M. Hanaki, S. Kato and Y. Kubota is also gratefully acknowledged.

Potential conflict of interest

Disclosure forms provided by the authors are available with the full text of this article online at https://dx.doi.org/10.1080/10428194.2018.1427862.

Additional information

Funding

This study was funded by JSPS KAKENHI Grant Number JP16K07457 and the Grant-in-Aid for Cancer Research (21-8-5) from the Ministry of Health, Labor and Welfare, Japan.

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