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Leukemia & Lymphoma Volume 63, 2022 - Issue 13
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Letters to the Editor

Single and multiple point NRAS mutations in acute myeloid leukemia: a study of 327 well molecularly characterized patients

Anna Durinikovaa Department of Internal Medicine – Hematology and Oncology, University Hospital Brno, Brno, Czech Republic;b Department of Internal Medicine – Hematology and Oncology, Faculty of Medicine, Masaryk University, Brno, Czech RepublicView further author information
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Adam Foltaa Department of Internal Medicine – Hematology and Oncology, University Hospital Brno, Brno, Czech RepublicORCID Iconhttps://orcid.org/0000-0001-6509-6902View further author information
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Filip Pardyc Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech RepublicView further author information
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Jan Svatona Department of Internal Medicine – Hematology and Oncology, University Hospital Brno, Brno, Czech Republic;c Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech RepublicView further author information
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Marie Drncovaa Department of Internal Medicine – Hematology and Oncology, University Hospital Brno, Brno, Czech Republic;b Department of Internal Medicine – Hematology and Oncology, Faculty of Medicine, Masaryk University, Brno, Czech RepublicORCID Iconhttps://orcid.org/0000-0002-5246-8372View further author information
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Barbora Weinbergerovaa Department of Internal Medicine – Hematology and Oncology, University Hospital Brno, Brno, Czech Republic;b Department of Internal Medicine – Hematology and Oncology, Faculty of Medicine, Masaryk University, Brno, Czech RepublicORCID Iconhttps://orcid.org/0000-0001-6460-2471View further author information
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Petr Cetkovskyd Institute of Hematology and Blood Transfusion, Prague, Czech RepublicView further author information
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Zdenek Racild Institute of Hematology and Blood Transfusion, Prague, Czech RepublicORCID Iconhttps://orcid.org/0000-0003-3511-4596View further author information
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Pavel Jindrae Department of Hematology and Oncology, University Hospital Pilsen, Pilsen, Czech RepublicView further author information
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Tomas Szotkowskif Department of Hemato-Oncology, University Hospital Olomouc, Olomouc, Czech RepublicView further author information
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Pavel Zakg Department of Internal Medicine – Department of Hematology, University Hospital Hradec Kralove, Hradec Kralove, Czech RepublicORCID Iconhttps://orcid.org/0000-0002-8415-7069View further author information
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Jiri Mayera Department of Internal Medicine – Hematology and Oncology, University Hospital Brno, Brno, Czech Republic;b Department of Internal Medicine – Hematology and Oncology, Faculty of Medicine, Masaryk University, Brno, Czech Republic;c Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech RepublicORCID Iconhttps://orcid.org/0000-0003-0567-9887View further author information
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Ivana Jeziskovaa Department of Internal Medicine – Hematology and Oncology, University Hospital Brno, Brno, Czech Republic;b Department of Internal Medicine – Hematology and Oncology, Faculty of Medicine, Masaryk University, Brno, Czech RepublicCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-8760-7718View further author information
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Pages 3237-3240 | Received 06 Apr 2022, Accepted 15 Aug 2022, Published online: 01 Sep 2022
 
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Acknowledgements

CEITEC Masaryk University’s Core Facility Genomics is gratefully acknowledged for obtaining the scientific data presented in this paper.

Author contributions

AD, AF, and IJ designed the study. AD, AF, FP, and MD performed the experiments. AD, AF, FP, JS, and IJ analyzed the data. AD, AF, FP, JS, and IJ wrote the manuscript. BW, PC, ZR, PJ, TS, PZ, and JM provided the patient samples and clinical data. MD, BW, PC, ZR, PJ, TS, PZ, and JM revised the article. All authors read and approved the final manuscript.

Disclosure statement

The authors declare no conflict of interest.

Additional information

Funding

This work was supported by the Ministry of Health of the Czech Republic, Grant No. 15-25809A, Ministry of Education, Youth and Sports of the Czech Republic, Project No. MUNI/A/1330/2021, and the Ministry of Health of the Czech Republic, No. FNBr, 65269705.

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