Author contributions
Chengyuan Gu and Qian Wu contributed to manuscript preparation, data acquisition, and clinical treatment. Jingren Zhang contributed to the collection of clinical data and clinical treatment. Liqing Kang and Lei Yu contributed to CAR-T cell preparation. Depei Wu contributed to data acquisition and interpretation and design. Xiaofei Yang and Suning Chen contributed to the study design, data analysis, and manuscript revision.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Additional information
Funding
The authors thank all members of the study team, the patients, and their family. This work was supported by research grants from the National Natural Science Foundation of China [81730003], National Science and Technology Major Project [2017ZX093040 21], National Key R&D Program of China [2019YFC0840604, 2017YFA0104502], National Natural Science Foundation of Jiangsu Province [BE2018652], Key R&D Program of Jiangsu Province [BE2019798], Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD), Jiangsu Medical Outstanding Talents Project [JCRCA2016002], Jiangsu Provincial Key Medical Center [YXZXA2016002], Suzhou Science and Technology Program Project [SLT201911].