Photo-physical aspects of BODIPY-coumarin conjugated sensor and detection of Al³⁺ in MCF-7 cell

ABSTRACT

BODIPY azine bearing chemosensor R1 has been synthesised for selective detection of Al³⁺with visual colour change from red-purple to purple and photo-physical studies were explained through Förster Resonance Energy Transfer (FRET) mechanism. Chemosensor showed good sensing capability with high binding constant and lower Limit of Detection (LOD) towards Al³⁺. Cell viability and fluorescence microscopic experiments illustrated about the cytocompatibily of the sensor in presence of Al³⁺ in living cells (MCF-7).

Graphical abstract

KEYWORDS:

• Chemosensor
• FRET
• Al³⁺ and cell image

Acknowledgments

SD acknowledges SERB-DST, Govt. of India, for financial assistance (project no. EMR/2016/002183) and DST- FIST (project no. SR/FST/CSI-256/2013). KSK are thankful to IIT (ISM), Dhanbad for providing fellowship. SKH acknowledges DST-SERB, New Delhi, (project No. ECR/2016/0105), USIC, DST-FIST & DST-PURSE for providing research facilities.

Disclosure statement

No potential conflict of interest was reported by the authors.

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