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Amyloid
The Journal of Protein Folding Disorders
Volume 15, 2008 - Issue 3
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Letter to the Editor

Bullous lesions of the vulvar region revealing both AL amyloidosis and vulvar carcinoma

H. P. Van De Nieuwenhof Departments of Obstetrics & GynecologyCorrespondence[email protected]
,
A. J. Croockewit Hematology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands
,
I. A. M. Van Der Avoort Departments of Obstetrics & Gynecology
,
R. L. M. Bekkers Departments of Obstetrics & Gynecology
&
J. A. De Hullu Departments of Obstetrics & Gynecology
Pages 210-212 | Published online: 06 Jul 2009
 
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Abstract

We report a patient with a bullous disorder which revealed both AL amyloidosis and a vulvar squamous cell carcinoma. Bullous amyloidosis is the rarest clinical manifestation of the amyloidoses, and is usually accompanied by systemic amyloid deposition with multiorgan involvement. This case illustrates that a localized disorder can trigger the diagnosis of a systemic disease.

Abbreviations
SCC=

squamous cell carcinoma;

AL amyloidosis=

light chain amyloidosis

Abbreviations
SCC=

squamous cell carcinoma;

AL amyloidosis=

light chain amyloidosis

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