Declaration of interest
The THAOS registry and the analyses presented here are sponsored by Pfizer. Editorial support was provided by Diane Hoffman, PhD and Mary Kunjappu, PhD of Engage Scientific Solutions and was funded by Pfizer. MWC has received support from Pfizer to act as a clinical trial investigator, for travel expenses to attend scientific meetings, and to act as a consultant. FB has received support from Pfizer for scientific meeting expenses. MWC, AG-D, and FB are THAOS scientific board members. RM and M-LO are full-time employees of Pfizer and hold stock and/or stock options.