Reproductive outcomes following a ruptured ectopic pregnancy

Abstract

Purpose: To determine the effect of ruptured ectopic pregnancies on the rate of future intrauterine pregnancies.

Materials and Methods: This was a retrospective study of patients at a University-affiliated hospital with a history of an ectopic pregnancy between January 1991 to December 2016. All patients that underwent a salpingectomy for a tubal ectopic pregnancy were considered for this study. Intrauterine pregnancy rates for patients with a history of a ruptured ectopic pregnancy were compared to those with non-ruptured ectopic pregnancies. Fisher’s exact test was used for analysis.

Results: During the study period, 77 patients met the inclusion criteria. In this cohort, 14 patients with a history of a tubal ruptured ectopic pregnancy had achieved pregnancy within 12 months, compared to 24 patients in the non-ruptured group (52% vs 48%, p = 0.81). The rate of intrauterine pregnancies, compared to repeat ectopic pregnancy, in both the ruptured and non-ruptured group, was 71% (p > 0.99).

Conclusion(s): Ruptured ectopic pregnancies did not adversely affect the rate of intrauterine pregnancy within 12 months of rupture when compared to non-ruptured ectopic pregnancies.

摘要

目的：确定异位妊娠破裂对未来宫内妊娠率的影响。

材料与方法：本研究是对1991年1月至2016年12月期间有宫外孕史的大学附属医院患者的回顾性研究, 所有接受输卵管切除术治疗输卵管异位妊娠的患者均考虑进行本研究。将有宫外孕破裂史的患者的宫内妊娠率与未破裂的异位妊娠患者进行比较, Fisher的精确检验用于分析。

结果：在研究期间, 77名患者符合纳入标准, 在这个队列中, 14例有输卵管破裂异位妊娠史的患者在12个月内实现了妊娠, 而未破裂组有24例患者（52%vs 48%, p=0.81）；与重复异位妊娠相比, 破裂组和未破裂组的宫内妊娠率均为71%（p>0.99）。

结论：与未破裂的异位妊娠相比, 破裂的异位妊娠在破裂后12个月内不会对宫内妊娠率产生不利影响。

Keywords:

• Fertility outcomes
• salpingectomy
• tubal pregnancy
• maternal outcomes

Disclosure statement

There are no conflicts of interest to disclose.

Author contributions

BP and DH conceived and designed the study, collected and analysed the data and drafted the manuscript. KG and RK analysed the data and critically revised the manuscript. All authors approved the final version of the manuscript.