Abstract
This study aimed to assess the association of menstrual blood volumes (MBV) and reproductive outcomes in patients after uterine artery embolization (UAE) combined with curettage for caesarean scar pregnancy (CSP). This retrospective observational study enrolled women who underwent UAE plus curettage for CSP at the Interventional Department of Henan Provincial People’s Hospital between December 2012 and December 2017. The primary outcome was pregnancy rate and the secondary outcomes were live birth rate (LBR) and interpregnancy interval. This study finally included 37 women (16 women with normal MBV and 21 women with decreased MBV) with pregnancy intention after UAE plus curettage for CSP. The pregnancy rate in women with normal MBV was higher than those with decreased MBV (81.3% vs. 47.6%; P = 0.048). There were no differences between the two groups regarding the interpregnancy interval (18.4 ± 8.7 vs. 22.2 ± 10.0 months, P = 0.233), and LBR (63% vs. 38%, P = 0.191). In conclusion, Women with normal MBV after UAE combined with curettage for CSP management might have a higher pregnancy rate compared with patients with decreased MBV, but there were no differences in LBR between the two groups.
Acknowledgements
Thanks to Jingge Zhao from the Clinical Research Center of Henan Provincial People’s Hospital for statistical analysis of the data in this study.
Ethics approval and consent to participate
This study was approved by the Ethics Committee of Henan Provincial People’s Hospital. All patients provided written informed consent. All methods are carried out in accordance with relevant guidelines.
Author contributions
Conception and design: CGS, LRQ; Administrative support: LJW; Provision of study materials or patients: LJ; Collection and assembly of data: LYY, LLP; Data analysis and interpretation: ZXY, LH, CHC; Manuscript writing: All authors; Final approval of manuscript: All authors.
Disclosure statement
The authors report there are no competing interests to declare
Availability of data and materials
The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request.