Non-identified and directed embryo donation: a questionnaire study on donor and recipient perspectives

Abstract

With the growing challenge of abandoned surplus embryos in the ART arena, and the limited traction of embryo donation as a viable embryo disposition choice, it is important to better understand barriers to wider adoption of this opportunity. We aim to learn about perspectives and experience of participants in directed and non-identified embryo donation programmes. This was a longitudinal cohort survey study, of all participants in an embryo donation programme in a single university affiliated clinic between 2016 and 2020. Clinical data were extracted from counselling reports. Based on these data, non-identified online questionnaires were constructed and refined via Delphi procedure for face and content validity. Sixty-five online questionnaires were emailed between March-April 2021. Descriptive statistics, cross-tabulation, Fisher’s exact test and t-test were used for analyses. Source of patient awareness, factors influencing the decision-making process, patient perspective and satisfaction were explored. The response rate was 67.2%. Most participants in the non-identified programme learned of it through their treating physicians, whereas most participants in the directed programme learned of it online. The main driver to donate across both cohorts was wanting to give others the opportunity to experience the joy of parenthood. Overall, 45% described moderate to marked difficulty in decision making related to donating their embryos, and this did not differ between cohorts. Non-identified donors reported feeling highly attached to the donated embryos more often than directed donors. Level of satisfaction was higher in the directed donation programme. Participants were more satisfied following directed than non-identified donation, and some even consider their counterparts as extended family. Our findings should be validated in various settings, and on larger samples.

Keywords:

• Direct to consumer genetic testing
• surplus embryos
• embryo donation
• direct and non-identified embryo donation
• donation disclosure preferences
• embryo disposition
• donated embryos

Acknowledgments

The authors acknowledge all patients who participated in this study and provided their input to help us better understand the strengths and pitfalls of embryo donation as it is offered at our clinic.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

These findings were presented at the CFAS 67th Annual Meeting on September 23rd-25th, 2021 – at the Westin Bayshore Hotel; Vancouver, British Columbia.