Prevention of early onset group B streptococcal disease: controversial issues

Abstract

Intrapartum chemoprophylaxis is currently the most effective preventive strategy against the neonatal early-onset group B streptococcal infection. The principal controversies on strategies for intrapartum antibiotic administration, possible adverse effects, management of newborn and possible future preventive strategies reported in the literature are considered.

Keywords:

• Group B streptococcus
• early onset neonatal sepsis
• neonatal infection
• streptococcal prevention
• intrapartum antibiotic
• vaccine