Influencing factors for placenta accreta in recent 5 years: a systematic review and meta-analysis

Abstract

Objective

Assess influencing factors for placenta accreta in pregnant women documented in recent literature.

Methods

A systematic review and meta-analysis were conducted based on English- and Chinese-language articles published from January 2014 to June 2019. Articles were retrieved from the following Chinese databases, CNKI, Wanfang Data, China Science and Technology Journal Database, CBM and English databases, PubMed, Web of Science, the Cochrane Library and Embase.

Results

Eleven studies with 2,152,014 cases were included in the meta-analysis. The odds ratios of influencing factors were as follows: hypertension 2.51 (95% CI, 1.50–4.20), multifetal gestations 1.90 (95% CI, 1.26–2.88), male fetus 0.79 (95% CI, 0.74–0.84), and low socioeconomic status 0.51 (95% CI, 0.37–0.71).

Conclusion

Evidence from English- and Chinese-language literature indicates that hypertension and multifetal gestations are risk factors for placenta accreta, while male fetus and low socioeconomic status are protective factors.

Keywords:

• Placenta accreta
• influencing factors
• meta-analysis
• cesarean section
• postpartum hemorrhage

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This work was supported by the Hunan Key Laboratory of Nursing Science [grant number 2017TP1004] and Clinical Nursing Research Foundation of the Second Xiangya Hospital of Central South University [grant number 2017-YHL-25].