Pregnancy outcomes among symptomatic and asymptomatic women infected with COVID-19 in the west of Iran: a case-control study

Abstract

Background

The purpose of this study was to investigate pregnancy outcomes among symptomatic and asymptomatic women infected with coronavirus disease 2019 (COVID-19) in the west of Iran.

Materials and methods

In this case-control study, 45 pregnant women infected with symptomatic COVID-19 were compared with 45 pregnant women infected with asymptomatic COVID-19. The cases included women were referred for delivery to hospitals of Hamadan Province and infected with COVID-19-related symptoms. The diagnosis of COVID-19 was based on the results of real-time reverse-transcriptase polymerase-chain-reaction (rRT-PCR) detection. The control group included asymptomatic women who were referred for delivery to hospitals in Hamadan Province infected with COVID-19. Data were collected by a checklist. For the data analysis, the Stata version 12 was used (StataCorp, College Station, TX).

Results

The odds of cesarean delivery in symptomatic women was more the fourfold higher (OR = 4.12, 95% CI (1.7, 10.05), p = .002). Moreover, the odds of LBW was significantly higher in symptomatic women (OR = 2.1, 95% CI (1.2, 6.29), p = .035).

Conclusions

Our findings showed that cesarean delivery and LBW were significantly higher in symptomatic women compared with asymptomatic women. In areas with high COVID-19 pandemics, the performance of the PCR test is recommended for all pregnant women upon admission for delivery.

Keywords:

• Coronavirus; pregnancy outcomes; symptomatic; asymptomatic
• case-control

Acknowledgements

The protocol of this study was confirmed in Hamadan University of Medical Sciences with the code: 9906113698.

Disclosure statement

No potential conflict of interest was reported by the author(s).