Middle-East OBGYN Graduate Education (MOGGE) Foundation practice guidelines: prevention of group B Streptococcus infection in pregnancy and in newborn. Practice guideline no. 02-O-20

Abstract

Rectovaginal colonization with group B streptococcus (GBS) is commonly encountered in pregnancy. GBS is the most common cause of early onset neonatal sepsis, which is associated with 12% case-fatality rate. Although screening protocols and prophylactic treatment are readily available worldwide, practice in low-resource countries is challenged by lack of awareness and limited implementation of these protocols. In addition, antibiotic susceptibility pattern may vary globally owing to different regulations of antibiotic prescription or prevalence of certain bacterial serotypes. This guideline appraises current evidence on screening and management of GBS colonization in pregnancy particularly in low-resource settings.

Keywords:

• Low-resource setting
• obstetrics
• neonatal sepsis
• neonatal infection
• antibiotic susceptibility

Acknowledgement

Middle-East Obstetrics and Gynecology Graduate Education (MOGGE) Foundation Practice Committee would like to thank Dr. AbuBakr Elnashar for providing input and advice on the final version of the manuscript, and would like to thank Dr. Mohamed Sabry, Dr. Shaimaa Gamal, and “up to date in obstetrics and gynecology” workgroup for facilitating provider-based surveys.

Disclosure statement

No potential conflict of interest was reported by the author(s).