Identification of sesquiterpene coumarins of oleo-gum resin of Ferula assa-foetida L. from the Yasuj region

Abstract

Chemical investigation of the oleo-gum resin of Ferula assa-foetida L. from Yasuj region led to the identification of five sesquiterpene coumarins namely, conferone (1), badrakemin (2), feslol (3), isosamarcandin (4) and samarcandin (5). The compounds were characterised by detailed 1D (¹H and ¹³C) and 2D NMR (HMBC, HSQC and NOESY) experiments. Among these compounds, conferone (1) and isosamarcandin (4) are being newly reported in F. assa-foetida L.

Keywords:

• Ferula assa-foetida
• oleo-gum resin
• sesquiterpene coumarin
• column chromatography

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This investigation was supported by a M.Sc. grant from Golestan University.