Numerical study on the effect of bifurcation vessel parameters on microwave ablation of lung tissue

ABSTRACT

Background: In order to study the effect of bifurcation vessels parameters on the temperature field and coagulation zone of microwave ablation on lung tissue. Methods: The finite element method was used to establish the simulation model. The angle of bifurcation vessel model was 60°. The position of the antenna and the main blood vessel are parallel, and the distance between them was 5, 10 and 15 mm, respectively. Temperature field distribution was obtained at 2450 MHz, 50 W and 300 s. The blood flow velocity was set to 0.1 and 0.2 m/s. Results: The results showed when the antenna was 5 mm away from the bifurcation vessel and the velocity was 0.1 m/s, the position of x = 8.4 mm achieved the complete necrosis at 220 s, while the fraction of necrotic tissue at the symmetry point x = 1.6 mm was 0.2 at 300 s. For the distance was 10 mm and the velocity was 0.1 m/s, the fraction of necrotic tissue at x = 3 mm that near the bifurcation vessel was 0.53 and was 0.69 at the symmetry point x = 17 mm. When the antenna is 15 mm away from the vessel, the fraction of necrotic tissue of symmetrical points on both sides of the antenna obtained after ablation were the same. Conclusions: The distance between the antenna and the bifurcation vessel over 15 mm, the blood flow has no effect on the coagulation zone. Besides, the distance between bifurcation vessel and antenna possesses a greater influence on the temperature distribution and coagulation zone than the blood flow velocity.

KEYWORDS:

• Microwave ablation
• lung tissue
• bifurcation vessel
• blood velocity
• temperature distribution
• coagulation zone

Disclosure statement

No potential conflict of interest was reported by the author(s).

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Additional information

Funding

This research was funded by the National Natural Science Foundation of China (Grant Nos. 31771021 and 11832003), and Jiangsu Science and Technology Foundation(Grant Nos. BE2017758).