Crystal, molecular structure, and conformational preferences of 3-(2-(4-morpholinophenyl)-2-oxoethyl)-5,5-diphenylimidazolidine-2,4-dione

ABSTRACT

The X-ray crystal structure of 3-(2-(4-morpholinophenyl)-2-oxoethyl)-5,5-diphenylimidazolidine-2,4-dione (2) [C₂₇H₂₅N₃O₄: MF = 455.50, monoclinic, P2₁/c, a = 6.2038 (2) Å, b = 20.8905 (6) Å, c = 18.3361 (6) Å, b = 97.594 (2)^ο, V = 2355.53 ų, Z = 4, D_calc = 1.284 Mg m⁻³, λ = 1.54178 Å] was determined. The crystal packing confirmed the occurrence of two conformers of opposite conformation. Conformational aspects of compound 2 have pointed out two factors that determine the conformation of the system under investigation: first, the intermolecular hydrogen bonding of the crystal packing, which stabilizes and favors the occurrence of two independent molecules, and the second factor is the steric hindrance among substituents.

KEYWORDS:

• Imidazolidine-2,4-dione
• UV-spectra
• X-ray crystal structure
• crystal pack
• conformers

Funding

The authors extend their appreciation to the Deanship of Scientific Research at King Saud University for funding the work through the research group project No. RG-1435-046.