Gestational Outcomes of Pregnant Women with Unilateral Congenital Renal Agenesis

Abstract

Objective

We evaluated if there were more adverse gestational outcomes of pregnant women with unilateral congenital renal agenesis (UCRA). Study design: This single center retrospective case–control study compared maternal complications and neonatal outcomes from 25 women with UCRA to the outcomes of 125 women with two kidneys. Results: UCRA women had lower gestational weeks at birth and higher rates of preterm delivery (p = 0.004 and <0.001; respectively). Mothers had higher rates of preeclampsia and newborns with congenital anomalies and neonatal intensive care unit (NICU) admission (p = 0.009, 0.042, and 0.039; respectively). Unadjusted odds ratios were significantly higher for preterm delivery and for any APGAR score of <7 at the first 10 min and preeclampsia [OR (95% CI):13.5 (4.66–39.05), 31 (3.44–279.32) and 5.76 (1.33–24.84), respectively]. Conclusion: Maternal UCRA is a risk factor for less optimal obstetric and neonatal outcomes.

Keywords:

• unilateral congenital renal agenesis
• preterm birth
• preeclampsia
• congenital anomaly
• perinatal morbidity

Disclosure statement

The authors declare no conflict of interest.