Abstract
Background/objective
Neonatal skin conditions are typically diagnosed through noninvasive methods. Few studies describe the spectrum of biopsy- evaluated neonatal skin lesions. We present our institutional experience with the conditions leading to skin biopsies in neonates. The objective is to describe the conditions for which skin biopsies are performed in neonatal patients.
Methods
There were 20 neonatal skin biopsies over a 10-year period from the hospital’s delivery unit, NICU, and pediatric hospital. Biopsies were categorized as inflammatory (not caused by an infectious agent), congenital, neoplastic, infectious, and vascular conditions.
Results
The patients’ ages ranged from 1 day to 4 weeks, with a male predominance. There were 6 inflammatory, 7 congenital, 5 neoplastic, 1 infectious, and 1 vascular lesions.
Conclusions
The most frequent neonatal skin biopsy lesions were inflammatory or congenital lesions. This review described the types of neonatal dermatopathology specimens that we encountered in practice.
Authors contributions
Dr. Allie Preston primarily oversaw task delegation and was a main author of the manuscript. Cynthia Lee, BS, was responsible for conducting a comprehensive chart review, organizing database information, and also held a key role as a main manuscript author. Drs. Martin Fernandez and Sophia Hendrick took an essential role as manuscript editors.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Data availability Statement
The authors confirm that the data supporting the findings of this study are available within the article.