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Clinical Toxicology Volume 45, 2007 - Issue 1
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Case Report

Cocaine-related peripheral vascular occlusive disease treated with iloprost in addition to anticoagulants and antibiotics

Antonino Mazzone Azienda Ospedale di Legnano, Presidio di Legnano, UO Medicina II, Legnano, Italy
,
Leopoldo Giani Azienda Ospedale di Legnano, Presidio di Legnano, UO Medicina II, Legnano, Italy
,
Paola Faggioli Azienda Ospedale di Legnano, Presidio di Legnano, UO Medicina II, Legnano, Italy
,
Simona Pichini Drug Research and Evaluation Department, Istituto Superiore di Sanità, Roma, Italy
&
Roberta Pacifici Drug Research and Evaluation Department, Istituto Superiore di Sanità, Roma, Italy
Pages 65-66 | Received 02 May 2005, Accepted 22 Jul 2005, Published online: 07 Oct 2008
 
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Abstract

We describe a case of acute ischemia of the 2nd, 3rd and 4th fingers of the right hand secondary to peripheral vascular occlusive disease induced by repeated intra-arterial cocaine injections. The complete occlusion of the distal arteries resolved following treatment with iloprost, a synthetic stable analogue of prostacyclin PGI2, in addition to anticoagulants and antibiotics.

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