Aging of the skin in pseudoexfoliation syndrome

ABSRACT

Background

It was reported that pseudoexfoliative material deteriorates iris, brain, heart and lung functions. This material is also found in the skin.

Aims

The purpose of this study was to investigate the possible effects of pseudoexfoliation material on the aging of the facial skin.

Study design

Cross-sectional study.

Methods

Forty pseudoexfoliation syndrome (PES) cases and 40 age- and gender-matched controls were evaluated. Job, cigarette use and the presence of any systemic diseases as well as the duration of sun exposure for all the cases were recorded. All of the cases underwent facial skin examination with Wrinkle Assessment Scale as per Lemperle G et al. and Pinch Test.

Results

Wrinkle Assessment Scale scores of the groups also were compared for all 8 facial locations. There were statistically significant differences found between Wrinkle Assessment Scale scores in PES and Control Group for all 8 locations. Mean Wrinkle Assessment Scale scores of women were 4.12 ± 0.74 in Control Group and 4.75 ± 0.37 in PES group (p = 0.0001). For men, mean Wrinkle Assessment Scale scores were 3.77 ± 0.72 in Control group and 4.54 ± 0.36 in PES group (p = 0.002).

Conclusion

These results implies that there is quicker progression in aging of facial skin in PES than normals.

Keywords:

• Pseudoexfoliation syndrome
• facial skin
• wrinkle
• aging

Authors’ contribution

Conceptualization: HC, HİY Formal analysis: HC, HİY. Funding acquisition: HC, HİY Investigation: HC, HİY. Methodology: HC, HİY. Project administration: HC, HİY Resources: HC, HİY Software and visualization: HİY Writing—review and editing: HC, HİY

Disclosure statement

No potential conflict of interest was reported by the authors.