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Abstract
Bisphenol-A (BPA) is a synthetically manufactured phenolic substance that is very widely employed in producing polycarbonate polymers and epoxy resins which further can be found in numerous items of daily use such as foodstuff and their containers, beverages, milk, audit rolls, dental fillings and so forth. Additionally, it is present in the air we breathe-in. The studies have reported that BPA produces toxic impacts on reproductive, cardiovascular, endocrine, renal, gastrointestinal, immune, respiratory, nervous and skeletal system. In the current literature review, we have targeted to highlight the protective role of herbs in opposition to BPA toxicity. The gift of nature-’Plants’ seem to be very efficient and potential agents to overcome the BPA induced toxicity as they themselves are devoid of adverse effects. Plants contain a mixture of phyto-molecules which together act to provide a synergistic effect. Further, we have explained the signaling mechanisms implicated in BPA toxicity. Even though, multiple mechanisms involved in BPA toxicity have been examined, no particular target therapy for this toxicity is available at present. Thus, naturally occurring substances may be looked at in the future for restorative use to mitigate the deleterious and negative consequences of exposure to BPA.
Acknowledgements
The authors are highly grateful to the Director Dr. (Col.) A.Garg and Joint Director, Dr. Manoj Goel, KIET Group of Institutions, Ghaziabad for their motivation and all-round support.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Research involving human participants and/or animals
Neither the animals nor the humans were involved in this study.