ABSTRACT
One hundred eighty-four asthmatic children were selected from 8 schools in Tainan City (high PM10 [particulate matter with aerodynamic diameter <10 μm] exposure) and Hualien County (low PM10 exposure) in Taiwan, and completed records of dietary consumption, daily peak expiratory flow rate (PEFR), and daily respiratory symptoms for 1 week. The higher prevalence of PEFR less than 80% predicted was found in children of high-exposure district than of low-exposure one, as well as in subjects with high intake of vitamin E than those who took less vitamin E. Furthermore, the risk of declining PEFR appeared to significantly decrease for subjects with both high intake of vitamins C and E and residing in area of low PM10 levels as compared with those with low intake of vitamins C and E and residing in high-exposure area. The beneficiary effect of vitamin C and E intake on PEFR improvement for asthmatic children with low air pollution is suggested.
Acknowledgments
The authors are indebted to the many children and their parents who participated in this study for their patience and understanding during the study. The authors’ appreciations also go to Dr Jiu-Yao Wang for his very valuable input and comments during the preparation of the manuscript. This study was, in part, supported by grant NSC92-2320-B-006-091.