Advanced search
Publication Cover
Infectious Diseases Volume 49, 2017 - Issue 11-12
Submit an article Journal homepage
162
Views
2
CrossRef citations to date
0
Altmetric
Original Article

Resistance phenotypes and susceptibility of contemporary Serratia isolates in the university hospital of Crete, Greece

George SamonisDepartment of Internal Medicine, University of Crete School of Medicine, Heraklion, Greece;
,
Konstantinos Z. VardakasAlfa Institute of Biomedical Sciences (AIBS), Athens, Greece; ;Department of Internal Medicine, Henry Dunant Hospital Center, Athens, Greece;
,
Sofia MarakiDepartment of Clinical Microbiology, University Hospital of Heraklion, Heraklion, Crete, Greece;
,
Petroula StamouliDepartment of Applied Mathematics and Physics, National Technical University of Athens, Athens, Greece;
,
Viktoria-Eirini MavromanolakiUniversity of Crete School of Medicine, Heraklion, Crete, Greece;
,
Diamantis P. KofteridisDepartment of Internal Medicine, University of Crete School of Medicine, Heraklion, Greece;
&
Matthew E. FalagasAlfa Institute of Biomedical Sciences (AIBS), Athens, Greece; ;Department of Internal Medicine, Henry Dunant Hospital Center, Athens, Greece; ;Department of Medicine, Tufts University School of Medicine, Boston, MA, USACorrespondence[email protected]
 show all
Pages 847-853 | Received 22 Mar 2017, Accepted 19 Jul 2017, Published online: 02 Aug 2017
 
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Abstract

Objective: To study changes in the susceptibility of Serratia spp. in Crete, Greece (2010–2015).

Methods: Non-duplicate isolates were examined using automated systems. Phenotypic confirmatory tests were applied.

Results: Three hundred and seventy-eight Serratia spp. were analyzed. Serratia marcescens (88.3%) was the predominant species. Fluoroquinolones (97.9%), carbapenems (97.4%) and fosfomycin (97.4%) were the most active followed by amikacin (95.5%), piperacillin/tazobactam (94.7%), and trimethoprim/sulfamethoxazole (94.4%). The activity of 3rd and 4th generation cephalosporins was 87–88.6%. The distribution of multi-drug resistant (MDR) strains varied, with a trend towards increasing frequency. ESBL (7.9%), carbapenemase (2.9%), AmpC (2.1%) and aminoglycoside modifying enzyme (10.6%) production were the commonest resistant phenotypes.

Conclusion: The susceptibility of Serratia spp. varied during the study period a trend towards decreasing susceptibility, especially for non-carbapenem β-lactams and aminoglycosides.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 174.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.