Biosynthesis of gold nanoparticles using sansevieria plant extract and its biomedical application

Abstract

The gold nanoparticles (Au NPs) are used for various medical applications including biosensors, bioassays, photo-thermal treatments, and targeted drug delivery. Au NPs are synthesized by various methods, most of them are expensive and environmentally hazardous. In this study, the biosynthesis of Au NPs was performed by Sansevieria extract. The synthesized nanoparticle was investigated by X-Ray Diffraction (XRD), field-emission scanning electron microscopes, Fourier transform infrared spectroscopy (FTIR), and the UV–visible spectroscopy. The results showed that Sansevieria extract could produce spherical Au NPs with a diameter of about 40-70 nm in an economical and environmentally friendly synthesis method. It was also indicated by the MTT assay that the Au-NPs had low cellular cytotoxicity and promoted the antiproliferation effect of Cisplatin on prostate cancer cells (LN Cap).

Keywords:

• Biosynthesis
• Au NPs
• Sansevieria plant

Disclosure statement

No potential conflict of interest was reported by the author(s).