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Chronobiology International
The Journal of Biological and Medical Rhythm Research
Volume 17, 2000 - Issue 4
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CIRCADIAN CHANGES OF HEART RATE IN WEST SYNDROME

Julio Ardura Departments of Pediatrics, University of Valladolid, SpainCorrespondence[email protected]
,
Jesus Andres Departments of Pediatrics, University of Valladolid, Spain
,
Alicia Muñoz Departments of Pediatrics, University of Valladolid, Spain
,
Miguel Revilla University of Valladolid, Spain
&
Paz Aragon Departments of Pediatrics, University of Valladolid, Spain
Pages 591-595 | Received 26 Jul 1999, Accepted 13 Dec 1999, Published online: 07 Jul 2009
 
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Abstract

Patterns of circadian and ultradian rhythms in the heart rate(HR) are described in a full-term baby with birth asphyxia and convulsions.A 24h HR recording was carried out at the age of 1, 15, 56, 289, and 295 days;West syndrome diagnosis was made when the patient was 3 months old. The HRshowed no circadian rhythm in the follow-up, whereas it is known that thecircadian rhythm appears in healthy infants at the age of 1 month and remainsthereafter. This observation may be an indirect indicator of the interferenceof West syndrome with centers of neurological maturity. (ChronobiologyInternational, 17(4), 591–595, 2000)

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