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Journal of Toxicology: Clinical Toxicology Volume 39, 2001 - Issue 4
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Research Article

Self-Poisoning with Colchicum autumnale L. Flowers

Dr. Vincent Danel Unité de Toxicologie Clinique, Département Pluridisciplinaire de Médecine, Centre Hospitalier Universitaire, BP, 217, Grenoble, Cedex 9, 38043, France
,
Vincent C. Danel Unité de Toxicologie Clinique, Département Pluridisciplinaire de Médecine, Centre Hospitalier Universitaire, BP, 217, Grenoble, Cedex 9, 38043, France
,
Jean-François D. Wiart Hôpital Calmette, Centre Hospitalier Universitaire, Lille, France
,
Gaëlle A. Hardy Unité de Toxicologie Clinique, Département Pluridisciplinaire de Médecine, Centre Hospitalier Universitaire, BP, 217, Grenoble, Cedex 9, 38043, France
,
Françoise H. Vincent Unité de Toxicologie Clinique, Département Pluridisciplinaire de Médecine, Centre Hospitalier Universitaire, BP, 217, Grenoble, Cedex 9, 38043, France
&
Nicole M-P. Houdret Hôpital Calmette, Centre Hospitalier Universitaire, Lille, France
Pages 409-411 | Published online: 31 Jul 2001
 
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Abstract

Case Report: A 44-year-old man ingested about 40 flowers of Colchicum autumnale L. The patient presented with nausea, vomiting, and abdominal pain 2 hours after ingestion and had diarrhea 14 hours after ingestion. Hematological values remained within normal range. Treatment was mainly supportive. The outcome was favorable. The intoxication was confirmed by high-performance liquid chromatography–mass spectrometry. Maximal colchicine levels were 4.34 ng/mL at 13 hours in plasma and 5.43 ng/mL at 16 hours in erythrocytes. Conclusion: We report one of the few symptomatic cases of Colchicum autumnale L. poisoning confirmed by toxicological analysis.

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