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Letter to the Editor

Comment on “Baclofen Withdrawal Following Removal of an Intrathecal Baclofen Pump Despite Oral Baclofen Replacement”

, M.D. & , M.D.
Page 1043 | Published online: 12 Mar 2003

To the Editor:

The informative article by Drs. Greenberg and Hendrickson Citation[1] quoted important safety information about intrathecal baclofen withdrawal that appears on the Medtronic, Inc. and US‐FDA Web sites.

We would like to inform the readers of the Journal of Toxicology, Clinical Toxicology that the sources for the Web‐based material are two articles that we published in 2001 and 2002 Citation[1]Citation[2]. Those articles contain more complete information on the topic, including an analysis of previously unpublished cases.

References

  • Greenberg M. I., Hendrickson R. G. Baclofen withdrawal following removal of an intrathecal baclofen pump despite oral baclofen replacement. J Toxicol Clin Toxicol 2003; 41(1)83–85
  • Coffey R. J., Edgar T. S., Francisco G. E., Graziani V., Meythaler J. M., Ridgely P. M., Sadiq S. A., Turner M. S. Abrupt withdrawal from intrathecal baclofen: recognition and management of a potentially life‐threatening syndrome. Arch Phys Med Rehabil 2002; 83: 735–741
  • Coffey R. J., Ridgely P. M. Abrupt intrathecal baclofen withdrawal: management of potentially life‐threatening sequelae. Neuromodulation 2001; 4: 142–146

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