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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 31, 2001 - Issue 1
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Original Articles

QUATERNARY AMMONIUM SALT-ASSISTED ORGANIC REACTIONS IN WATER: ALKYLATION OF PHENOLS

Jean Jacques Vanden Eynde Organic Chemistry Department, University of Mons-Hainaut, Place du Parc 20, B-7000, Mons, BelgiumCorrespondence[email protected]
&
Isabelle Mailleux Organic Chemistry Department, University of Mons-Hainaut, Place du Parc 20, B-7000, Mons, Belgium
Pages 1-7 | Published online: 09 Nov 2006
 
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Abstract

A series of quaternary ammonium salts has been tested as phase transfer agents to promote reactions between phenols and alkyl halides in an aqueous solution of sodium hydroxide in the absence oforganic solvent. Methyltrioctylammonium chloride emerges as the most effective catalyst.

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