Abstract
The first synthesis of tetracyclic isoflavone wrightiadione 1 was achieved through the benzylic oxidation of the key intermediate isoflavone 2 which in turn could be obtained by condensation of 2-indanone with methyl salicylate and LDA.
ACKNOWLEDGMENTS
Financial support from Thailand Research Fund (TRF) is gratefully acknowledged. The X-ray crystallographic analysis was kindly carried out by Dr. Palangpon Kongseri of Mahidol University.