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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 31, 2001 - Issue 18
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Original Articles

CONVENIENT SYNTHESIS OF RETINOL-RELATED POLYENES THROUGH HYDROXYALKYLATION OF 3-SULFOLENES

, &
Pages 2787-2793 | Received 28 Nov 2000, Published online: 15 Aug 2006
 

Abstract

Convenient synthesis of retinol-related polyenes is described through hydroxyalkylation of 3-sulfolenes followed by one-pot desulfonylation and dehydration in the presence of POCl3/pyridine in toluene.

ACKNOWLEDGMENTS

We (TS and SVB) thank Department of Science and Technology, New Delhi, India and (TS and TSC) thank the National Science Council of the Republic of China for financial support. We are grateful to RSIC and TIFR, Mumbai for spectral data.

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