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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 31, 2001 - Issue 18
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Original Articles

NOVEL SYNTHESIS OF CONDENSED HETEROCYCLIC SYSTEMS CONTAINING 1,2,4-TRIAZOLE RING

Zhongyi Wang Department of Chemistry, University of Science and Technology of China, Hefei, 230 026, P. R. China
,
Haoxin Shi Department of Chemistry, Anhui Normal University, Wuhu, 241 000, P. R. China
&
Haijian Shi Department of Chemistry, Nanjing University, Nanjing, 210 093, P. R. China
Pages 2841-2848 | Received 21 Nov 2000, Published online: 15 Aug 2006
 
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Abstract

3-Aryl-6,7-dihydro-s-triazolo[3,4-b][1,3]thiazines and 3-aryl-5,6-dihydro-thiazolo[2,3-c]-s-triazoles were synthesized by nucleophilic substitution of 3-aryl-5-mercapto-1,2,4-triazoles with 1,3-dibromopropane and 1,2-dichloroethane. And the bis-Mannich reaction of 3-aryl-5-mercapto-1,2,4-triazoles with formaldehyde has been studied.

ACKNOWLEDGMENTS

This work has been financially supported by Natural Science Foundation and Educational Committee Foundation of Anhui Province in P.R. China.

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