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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 31, 2001 - Issue 19
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Original Articles

SYNTHESIS OF SOME AMINO ACID ESTER LINKED DIOXATHIAPHOSPHOCIN/DIOXAPHOSPHOCIN DERIVATIVES

L. Nagaprasada Rao Department of Chemistry, Sri Venkateswara University, Tirupati, 517 502, India
,
C. Devendranath Reddy Department of Chemistry, Sri Venkateswara University, Tirupati, 517 502, India
,
V. Krishna Reddy Department of Chemistry, Sri Venkateswara University, Tirupati, 517 502, India
,
K. Ananda Kumar Department of Chemistry, Sri Venkateswara University, Tirupati, 517 502, India
&
C. Suresh Reddy Department of Chemistry, Sri Venkateswara University, Tirupati, 517 502, India
Pages 2929-2933 | Received 21 Aug 2000, Published online: 16 Aug 2006
 
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Abstract

Novel 6/8-amido(methoxyglycinyl/alaninyl)dioxathiaphosphocins/dioxaphosphocins (4, 7, 10) have been synthesized from reactions of monochlorides (3,6,9) with glycine methyl ester or alanine methyl ester hydrochlorides (1a,b) at room temperature in dry tetrahydrofuran in the presence of triethylamine.

ACKNOWLEDGMENTS

The authors express their thanks to Directors SIF, IISc Bangalore and CDRI, Lucknow, for spectral recording. L. N. Rao is thankful to UGC for awarding a fellowship.

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