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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 31, 2001 - Issue 19
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Original Articles

AN IMPROVED SYNTHESIS OF ENANTIOPURE β-AMINO ACIDS

, &
Pages 2943-2953 | Received 20 Sep 2000, Published online: 16 Aug 2006
 

Abstract

An improved method for the preparation of both the enantiopure β-amino acids is presented. The diastereomer benzyl β-amino esters, obtained by stereoselective reduction of β-enamino esters, were separated and hydrogenolyzed to the free enantiopure β-amino acids.

ACKNOWLEDGMENT

Financial support from Ministero dell'Università e della Ricerca-Scientifica e Tecnologica, Rome, and the University of Camerino (National Project “Stereoselezione in Sintesi Organica. Metodologie ed applicazioni”) is gratefully acknowledged.

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