Abstract
We described here an efficient and short new method to synthesize cyclopentanol derivatives. Ring opening of spiroepoxide 3 was done easily by an amine or ethyl carbamate leading to new molecules bifunctionalized. The characteristic 1H and 13C NMR spectroscopic features of the synthesized compounds are reported.
ACKNOWLEDGMENTS
We are grateful to MESR for a fellowship to F. Cachoux and to Dr. B. Vacher (Pierre Fabre Médicaments, Castres, Fr.) for helpful comments.