Unexpected Formation of Previously Unknown Cyclohex‐2‐enone Derivative via Carbonyl‐ene‐Synthesis at Room Temperature

Abstract

The unexpected formation of 6‐methyl‐2‐(2‐methylpropenyl)cyclohex‐2‐enone (6) during a deprotecting reaction of 1,3‐dioxane (5) via an interesting carbonyl‐ene reaction at room temperature with original aim to obtain 4,8‐dimethyl‐5‐oxonon‐6‐en‐1‐al (4) is reported. An alternative route to aldehyde (4) is also presented.

Keywords:

• Flash chromatography
• Carbonyl‐ene‐reaction
• Room temperature
• ¹H‐NMR and ¹³C‐NMR spectrum