Abstract
(R)‐(+)‐γ‐Jasmolactone (1b) was synthesized in 92% ee in two steps, starting from the easily prepared (S)‐(−)‐3‐(5‐oxo‐tetrahydro‐furan‐2‐yl)‐propionic acid benzyl ester (2). The key step features an inversion of configuration of the stereogenic center.
Acknowledgments
G. C. Clososki and L. J. Missio thank FAPESP for fellowships. J. V. Comasseto thanks FAPESP, CNPq, and CAPES for support.