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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 34, 2004 - Issue 21
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Original Articles

Preparation of Nitrogen Heterocycles of Spiro[Furo[2,3‐d]‐Pyrimidine]Pyrimidine Derivatives

Branko S. Jursic Department of Chemistry, University of New Orleans, New Orleans, Louisiana, 70148, USACorrespondence[email protected]
&
Edwin D. Stevens Department of Chemistry, University of New Orleans, New Orleans, Louisiana, 70148, USA
Pages 3915-3923 | Received 13 May 2004, Published online: 10 Jan 2011
 
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Abstract

The NMR evaluation of the reaction progression of the bromination of heterocyclic dibarbiturates was used to develop an efficient synthetic procedure for the preparation of heterocyclic spiro[furo]pyrimidines. The structure of one of these compounds was confirmed by X‐ray analysis.

Acknowledgment

We would like to thank the Louisiana Board of Regents (LEQSF(2001‐04)‐RD‐B‐12).

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