Abstract
Objective:
As part of the CHANGE PAIN international health campaign to improve pain management, patient surveys are being undertaken to explore how patients perceive their noncancer chronic pain and how they deal with it.
Research design and methods:
In Spain, 8695 patients completed this survey. The cross-sectional data were provided during routine visits to 893 physicians from different specialties. Pain intensity was assessed on two scales: a 5-point verbal rating scale (VRS) and an 11-point numerical rating scale (NRS).
Results:
Most patients were women (57%) in their late adulthood (45–64 years; 34%) or elderly (65 years or older; 53%). Pain duration of one year or longer was frequent (65%). Combined pharmacological treatment (51%) was more common than monotherapy (33%). The most frequently prescribed agents were nonsteroidal anti-inflammatory drugs, to be taken alone (18%) or together with weak opioids (15%), followed by weak (7%) or potent (6%) opioids in monotherapy; but there were many different treatments prescribed. Most patients had moderate (47%) or severe/extreme (34%) VRS rated pain. The mean intensity in the NRS was of 5.7 over 10. Many patients had pain above the level they could tolerate (38%) and most (55%) were not satisfied with their therapy. Their main goals were pain relief and reduction of side effects.
Key limitations:
Causal inductions are not possible in a cross-sectional research like this. Other clinically meaningful outcome measures in patients with chronic pain, such as patients’ quality of life, were not gathered.
Conclusions:
Chronic noncancer pain management is poor. The uncoupling of VRS and NRS pain ratings reveals the high subjectivity of the pain experience, whilst the wide variation in treatment choices indicates that an optimal management strategy remains to be defined. Advances might be attained by boosting communication to tailor treatments to individual patients’ perceptions.
Transparency
Declaration of funding
This research has been funded by Grünenthal Pharma S.A., Madrid, Spain.
Declaration of financial/other relationships
C.P. has disclosed that she is a consultant to Grünenthal, Mundipharma, Astellas, Boston Scientific, Takeda and Lilly. C.M. has disclosed that he is a consultant to Grünenthal, Astellas, Archimedes, Mundipharma and Pfizer. M.S. is a full-time employee of Grünenthal Pharma S.A.
CMRO peer reviewers may have received honoraria for their review work. The peer reviewers on this manuscript have disclosed that they have no relevant financial relationships.
Acknowledgements
The authors thank María Dolores Julián and Jesús Villoria who provided medical writing services.