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Abstract
Background: Neural stem cells (NSCs) hold the promise to cure a broad range of neurological diseases and injuries, particularly neurodegenerative diseases and spinal cord injuries. The recent confirmation that neurogenesis occurs in the adult brain and that NSCs reside in the adult CNS opens new opportunities and avenues for cellular therapy. Objectives: To provide an overview of the current patent situation related to NSCs and to highlight the limitations and challenges of bringing NSC research to therapy. Method: Reviewing the early studies and patents in NSC research. Conclusion: NSCs are in clinical trials for Batten and Parkinson's diseases. However, clinical development and other limitations will make it difficult for pharmaceutical/biotech companies to break even with these early patents.