Abstract
The area of antiulcer research has changed dramatically over the past three years due to the introduction of proton pump inhibitors and the discovery of the link between Helicobacter pylori and peptic ulcer disease. Established agents such as ranitidine and famotidine have secured their place in the world market, but a number of novel agents are currently under investigation and could lead to new therapies in the future. This article reviews the the existing treatments available and their side effects, whilst briefly discussing the new compounds which have been disclosed in the recent patent literature.