The following is a list of selected recently published Expert Opinion articles, related to the content of this issue of Expert Opinion on Investigational Drugs.
Adverse events associated with mTOR inhibitorsNicolas Pallet & Christophe LegendreMarch 2013, Vol. 12, No. 2, Pages 177-186(doi:10.1517/14740338.2013.752814)
The metabolic and toxicological considerations for mTOR inhibitors in the treatment of hepatocarcinoma
Francesca Ponziani, Veronica Ojetti, Annalisa Tortora, Luca Di Maurizio, Flaminia Purchiaroni & Antonio Gasbarrini
December 2011, Vol. 7, No. 12, Pages 1535-1546
(doi:10.1517/17425255.2011.631911)
Recent advances in the discovery of small-molecule ATP competitive mTOR inhibitors: a patent review
Arie Zask, Jeroen C Verheijen & David J Richard
July 2011, Vol. 21, No. 7, Pages 1109-1127
(doi:10.1517/13543776.2011.584871)
Cyclin-dependent kinase inhibitors closer to market launch?
Hervé Galons, Nassima Oumata, Olfa Gloulou & Laurent Meijer
Posted online on April 22, 2013
(doi:10.1517/13543776.2013.789861)
Cardiovascular toxicity of tyrosine kinase inhibitors
Elie Mouhayar, Jean-Bernard Durand & Jorge Cortes
Posted online on April 8, 2013
(doi:10.1517/14740338.2013.788642)
Recent understanding of the molecular mechanisms for the efficacy and resistance of EGF receptor-specific tyrosine kinase inhibitors in non-small cell lung cancer
Asuka Nakata & Noriko Gotoh
August 2012, Vol. 16, No. 8, Pages 771-781
(doi:10.1517/14728222.2012.697155)
Tyrosine kinase inhibitors in acute and chronic leukemias
Maro Ohanian, Jorge Cortes, Hagop Kantarjian & Elias Jabbour
May 2012, Vol. 13, No. 7, Pages 927-938
(doi:10.1517/14656566.2012.672974)
Cardiovascular toxicity associated with small molecule tyrosine kinase inhibitors currently in clinical use
Constantin A Dasanu, Premkumar Padmanabhan Bernard A. Clark 3rd & Christine Do
May 2012, Vol. 11, No. 3, Pages 445-457
(doi:10.1517/14740338.2012.672971)
Oral tyrosine kinase inhibitors in the first-line treatment of advanced non-small cell lung cancer
Bruno Gori, Serena Ricciardi, Ester Del Signore, Alberto Fulvi & Filippo de Marinis
April 2012, Vol. 16, No. S2, Pages S55-S60
(doi:10.1517/14728222.2011.652617)
Emerging FMS-like tyrosine kinase 3 inhibitors for the treatment of acute myelogenous leukaemia
Hillary Prescott, Hagop Kantarjian, Jorge Cortes & Farhad Ravandi
September 2011, Vol. 16, No. 3, Pages 407-423
(doi:10.1517/14728214.2011.568938)