Advanced search
Publication Cover
Expert Opinion on Biological Therapy Volume 9, 2009 - Issue 8
Submit an article Journal homepage
237
Views
21
CrossRef citations to date
0
Altmetric
Drug Evaluations

The role of natalizumab in hematopoietic stem cell mobilization

Frank Neumann Heinrich-Heine-University, Department of Hematology, Oncology and Clinical Immunology, Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany +49 211 8117720; +49 211 8118853; [email protected]
,
Fabian Zohren Heinrich-Heine-University, Department of Hematology, Oncology and Clinical Immunology, Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany +49 211 8117720; +49 211 8118853; [email protected]
&
Rainer Haas Heinrich-Heine-University, Department of Hematology, Oncology and Clinical Immunology, Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany +49 211 8117720; +49 211 8118853; [email protected]
Pages 1099-1106 | Published online: 01 Jul 2009
 
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Abstract

The humanized monoclonal very late antigen 4 (VLA-4) antibody natalizumab is FDA approved for the treatment of patients with multiple sclerosis and Crohn's disease. In this review we focus on its role in the context of hemato-poietic stem cell transplantation and stem cell diseases. The use of natalizumab alone or in combination with either cytotoxic drugs or other antibodies might be a new modality for stem cell mobilization and a therapeutic option for patients with hematologic malignancies.

Notes

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 99.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 960.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.