Acyclovir delivery systems

Abstract

Herpes viruses (herpes simplex, varicella zoster, cytomegalovirus) are the main cause of a wide variety of human infections. Although the development of successful antiviral agents against infections caused by herpes viruses had been slow until the last decade, the production of delivery systems for acyclovir are a promising alternative. The present review summarizes the principal advances made in developing carriers for the delivery of acyclovir by different routes of administration.

Keywords::

• acyclovir
• drug delivery
• drug formulations
• herpes simplex virus
• microparticles
• microemulsions
• nanoparticles
• vesicles

Acknowledgements

The authors acknowledge Regione Emilia Romagna (Spinner Project) and PRIN-2006 for financial support.