Abstract
Despite recent gains in screening and detection of breast cancer risk in postmenopausal women in the USA, there are still significant challenges in current risk assessment methods and patient management in premenopausal women. A finding of atypia in this patient population, with either a histological or cytological determination, has been shown to confer a four- to fivefold increase in relative risk for developing breast cancer. Currently, 75% of women in the USA who develop breast cancer have no identifiable risk factors, other than age. By screening a premenopausal, asymptomatic population in the obstetric gynecological setting, it is possible to find women at a significantly increased risk of developing breast cancer. Identifying women at increased risk will help clinicians and their patients to better make informed decisions regarding risk reduction and management options.
Financial & competing interests disclosure
Alan Hollingsworth served on the NeoMatrix Medical Advisory Board, and was compensated for his effort. John West has no competing interests. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.