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Expert Review of Anticancer Therapy Volume 9, 2009 - Issue 5
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Stereotactic body radiation therapy for oligometastases

Simon S Lo Associate Professor of Radiation Medicine and Neurosurgery, Director of Neuro-Radiation Oncology and Stereotactic Radiosurgery, Stereotactic Radiotherapy and Stereotactic Body Radiation Therapy, Residency Program Director, Department of Radiation Medicine, Arthur G James Cancer Hospital, Ohio State University Medical Center, 300 West 10th Avenue, Ste 088A, Columbus, OH 43210, USA. [email protected]
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Achilles J Fakiris Assistant Professor of Clinical Radiation Oncology, Department of Radiation Oncology, Indiana University Medical Center, 535 Barnhill Drive, RT041, Indianapolis, IN 46202, USA. [email protected]
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Bin S Teh Professor of Radiation Oncology, Director of Image-guided Radiation Therapy, Radiation Oncology Translational Research Program and Radiation Research Laboratory, Department of Radiation Oncology, The Methodist Hospital, 6565 Fannin, DB1-077, Houston, TX 77030, USA. [email protected]
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Higinia R Cardenes Professor of Clinical Radiation Oncology, Indiana University School of Medicine, Radiation Oncology Department, 535 Barnhill Drive, RT 041, Indianapolis, IN 46202, USA. [email protected]
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Mark A Henderson Assistant Professor of Clinical Radiation Oncology, Department of Radiation Oncology, Indiana University Medical Center, 535 Barnhill Drive, RT041, Indianapolis, IN 46202, USA. [email protected]
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Jeffrey A Forquer Resident, Department of Radiation Oncology, Indiana University Medical Center, 535 Barnhill Drive, RT041, Indianapolis, IN 46202, USA. [email protected]
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Lech Papiez Associate Professor of Radiation Oncology, Department of Radiation Oncology, University of Texas Southwestern Medical Center, 5801 Forest Park Road, Dallas, TX 75390, USA. [email protected]
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Ronald C McGarry Associate Professor of Radiation Medicine and Vice-Chair, Department of Radiation Medicine, 800 Rose Street, Room C114C, University of Kentucky, Lexington, KY 40536, USA. [email protected]
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Jian Z Wang Assistant Professor of Radiation Medicine; Director, Radiation Response Modeling Program, Department of Radiation Medicine, Arthur G James Cancer Hospital and Research Institute, The Ohio State University, 300 West 10th Avenue, Ste 094, Columbus, OH 43210, USA. [email protected]
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Kaile Li Assistant Professor of Radiation Oncology, Arthur G James Cancer Hospital and Richard J Solove Research Institute, Department of Radiation Medicine, The Ohio State University, 300 West 10th Avenue, Suite 094F, Columbus, OH 43210, USA. [email protected]
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Nina A Mayr Professor of Radiation Medicine, Department of Radiation Medicine, Arthur G James Cancer Hospital, The Ohio State University Medical Center, 300 West 10th Avenue, Suite 080, Columbus, OH 43210, USA. [email protected]
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Robert D Timmerman Professor of Radiation Oncology and Vice-Chair, Department of Radiation Oncology, University of Texas Southwestern Medical Center, 5801 Forest Park Road, NF3.302B, Dallas, TX 75390-9183, USA. [email protected]
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Pages 621-635 | Published online: 10 Jan 2014
 
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Abstract

The standard treatment for metastatic cancer is systemic therapy. However, in a subset of patients with limited extracranial metastases or oligometastases, local ablative therapy in combination with systemic therapy may improve treatment outcomes. Stereotactic body radiation therapy (SBRT) has emerged as a novel approach for local ablation of extracranial oligometastases. There is a good body of experience in the use of SBRT for the treatment of oligometastases in various sites including the lung, the liver and the spine with promising results. This article provides an overview of the use of SBRT in the management of extracranial oligometastases.

Financial & competing interests disclosure

Robert D Timmerman has received research grants from Varian Medical Systems and Elekta Oncology. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.

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