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Acta Obstetricia et Gynecologica Scandinavica Volume 89, 2010 - Issue 11
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SHORT REPORTS

First report on fertility after allogeneic uterus transplantation

César Díaz-García Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Obstetrics and Gynecology, La Fe University Hospital, University of Valencia, Valencia, SpainCorrespondence[email protected]
,
Shamima N. Akhi Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
,
Ann Wallin Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
,
Antonio Pellicer Department of Obstetrics and Gynecology, La Fe University Hospital, University of Valencia, Valencia, Spain; Instituto Universitario-Instituto Valenciano de Infertilidad IVI-Valencia, Valencia, Spain
&
Mats Brännström Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Pages 1491-1494 | Received 26 Aug 2010, Accepted 30 Aug 2010, Published online: 30 Sep 2010
 

Abstract

Uterus transplantation may become the first available treatment for uterine factor infertility, which is due to the absence or malfunction of the uterus. Here we describe for the first time pregnancy after allogeneic uterus transplantation, as a proof of concept of uterine function in a transplanted uterus in a standardized animal model (rat) under immunosuppression.

Acknowledgments

This research project was funded by the Swedish Research Council as well as by Jane and Dan Olsson Research Foundation. Dr. Diaz-Garcia is supported by grants from Salud 2000 Foundation and the Carlos III Health Institute.

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

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