Resolution of Severe Obsessive–Compulsive Disorder After a Small Unilateral Nondominant Frontoparietal Infarct

ABSTRACT

Obsessive–compulsive disorder (OCD) is a disabling neuropsychiatric disorder, which rarely spontaneously remits. We present a case of a patient suffering with severe OCD whose symptoms disappeared immediately following a small right posterior frontoparietal infarct. We speculate that the lesion modulated the cortical–subcortical circuits, likely through a change in input into in the dorsolateral prefrontal cortex. This could have implications regarding surgical targeting in OCD.

KEYWORDS::

• Obsessive–compulsive disorder
• stroke
• surgery
• target